Math Says Yes
Glossary term

Odds Ratio

A comparison of two groups made by dividing the odds of an event in one group by the odds in the other.

Visual intuition

before
2 cases
x2
after
4 cases
Odds ratio: 4-to-32 against 2-to-34, about 2.1
Cases rise from 2 to 4 in a group of 36. The x2 lens shows the risk ratio (4/36 versus 2/36). The odds ratio divides odds instead — 4 to 32 against 2 to 34, about 2.1 — nearly the same here because cases are rare (illustrative counts).

Formula

odds ratio = odds in group A / odds in group B

Example

If 50% of untreated patients recover ( 1 to 1) and 75% of treated patients do (odds 3 to 1), the odds ratio is 3 — even though the is only 1.5 (illustrative numbers).

How It Works

Take 36 people with 2 cases, and 36 with 4. The risks are 2/36 and 4/36, so the is 2.0. The are 2 to 34 and 4 to 32, so the odds ratio is (4/32) divided by (2/34) — about 2.1. When cases are rare, odds and risks nearly agree, which is why case-control studies — which by design can only estimate odds — still get reported as 'double the risk'. When the event is common, the odds ratio drifts away from the risk ratio and always looks more extreme: going from 50% to 75% recovery is a risk ratio of 1.5 but an odds ratio of 3.